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DMXE, or deoxymethoxetamine, is a relatively obscure research chemical that has not gained a lot of popularity yet. It is a member of the class of chemicals called arylcyclohexylamines which includes substances like ketamine and PCP.
How to use DMXE Powder
Arylcyclohexylamines are the oldest and most widely-used dissociative compounds on the planet. However, compared to popular and well-studied substances like ketamine, DMXE remains a relatively new arylcyclohexylamine.
Buy DMXE online in the highest quality powder form.
Ensure to store the DMXE powder in a dry and cool place for maximum shelf-life. When handling research chemicals ensure to always take the proper precautions in the laboratory like wiping down surfaces and wearing gloves, a mask & protective clothing.
The definition of DMXE is officially known as deoxymethoxetamine, is a novel compound in the arylcyclohexylamine group. It has not been circulating for very long and it hasn’t been recorded in the literature for very long.
These compounds are dissociative anesthetics with hallucinogenic properties. There are many different compounds in this category, the first of which were synthesized more than a century ago beginning with PCA, which was first recorded to be synthesized in 1907.
They vary from being fairly stimulating to relatively sedating. DMXE is relatively new and has not been researched very much, however, the research that has been done suggests it’s a little bit less potent than MXE while sharing a number of similarities in terms of duration and research effects.
If you buy DMXE powder it often comes in the form of small crystals that are almost sand-like with a tan/white appearance. However, we find that it is easier to provide researchers with pre-weighed DMXE pellets for simplicity.
Chemistry background information DMXE
The arylcyclohexylamine group consists of a cyclohexylamine unit with an aryl moiety attachment. The aryl group is positioned geminal to the amine. In the simplest compounds, the aryl moiety is simply a phenyl ring, perhaps with some substitution.
One of the reasons that there is so much variety among the arylcyclohexylamine is because of the way that hydrogen atoms in the structure can be substituted for other functional groups. This can produce a range of chemicals with wildly varying effects.
DMXE is structurally quite similar to MXE, however, the methoxy group is replaced with methyl (meaning that the oxygen has been replaced, hence giving rise to the deoxy in the substance’s name).
Research is still young in regards to DMXE. However, some researchers speculate that its potency can be determined by gauging the chemical process that leads to its creation.
When you add the ketone to 3-MeO-PCE, another popular research chemical arylcyclohexylamine, NMDAr potency is reduced by about 8.5 and sertraline affinity is reduced by about 3.5x.
Comparing these numbers to the affinities of MXE and the relative molecular changes, one could expect that it would be about 1.4x less potent as an NMDAr antagonist than MXE, and yet 1.2x more potent at the sertraline receptor site.
DMXE cannot be O-demethylated, however, which could lead to a longer onset and duration despite the decreased potency.
Where to buy DMXE online
Buy DMXE here on the Realchems website. We sell premium quality DMXE in powder and pellets form. However, we often have other substance forms available, so feel free to contact us to see if we have your preferred substance form in stock. You must be at least 18 years old to buy DMXE from us.
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